Mark Kuebel began his interest in medicine in the 1970's, graduating with a BA, Biological Sciences, concentrating in cell and molecular biology in 1982. He spent the next 10 years exploring art and medical sciences like homoeopathy and Western herbology. After the AIDS crisis personally impacted his circle of friends, he became a community activist, and turned his talents to medical research writing for AIDS organizations and promoting so-called alternative treatment for AIDS. He concurrently began research writing in the medical field as a freelancer. This increased exposure to alternative medicine lead him to acupuncture and Chinese herbology in 1992.

He started Chinese medicine education in 1994 in San Francisco, worked his way through school, graduating from the American College of Traditional Chinese Medicine in 2001, and returned to New York City that year. He has a private practice in the Union Square neighborhood of Manhattan, and focuses his talent in treatment of chronic illness: pain management, HIV, Hepatitis C, mental and emotional disturbances, and especially stress-induced illness. He currently is an instructor (since 2008) in three departments at the Pacific College of Oriental Medicine in Manhattan, NY. He teaches in the school Clinic, the Clinical Sciences and Western Science departments.